Applications of LOSWIFT Lactulose in Medical Health Industry
Lactulose as main component
mixed sugar solution
prebiotic properties
promotes intestinal health
Applications of LOSWIFT Lactulose in Medical Health Industry
What is LOSWIFT™Lactulose?
Natural Sweetness, Enhanced Performance
LOSWIFT™Lactulose (4-O-β-D-galactopyranosyl-D-fructose), also known as lactulitose, is a synthetic disaccharide with the molecular formula C₁₂H₂₂O₁₁ and a molar mass of 342.30 g/mol. LOSWIFT™Lactulose is produced by the isomerization of lactose under heated alkaline conditions. It consists of D-galactose linked to D-fructose via a β-1,4-glycosidic bond, making it an isomer of lactose.
The solid form exists as a white-to-off-white crystalline powder with a mild sweetness approximately 48%–60% that of sucrose. It is highly water-soluble (about 76.4 g/100 mL at 30 °C) and exhibits low viscosity, low caloric value, good heat and acid stability, and resistance to the Maillard reaction—making it easy to incorporate into a wide range of dosage forms.
Unlike artificial sweeteners, LOSWIFT™Lactulose resists hydrolysis by human gastric acid and small-intestinal digestive enzymes, meaning the molecule reaches the colon largely intact, where it is selectively fermented by the resident microbiota to provide natural benefits with clean properties.
Health Benefits
Constipation Relief
LOSWIFT™Lactulose is a classic osmotic laxative. After oral intake, it passes through the small intestine largely undigested, reaches the colon intact, and is metabolized by colonic bacteria into short-chain fatty acids. The resulting increase in intraluminal osmotic pressure draws water into the colon, softens the stool, and increases stool volume—providing gentle, well-tolerated relief of constipation.
Blood Ammonia Reduction and HE Support
Once fermented in the colon, LOSWIFT™Lactulose lowers intestinal pH, converting free ammonia (NH₃) into non-absorbable ammonium ions (NH₄⁺) and promoting the incorporation of ammonia into bacterial protein. This dual action reduces systemic ammonia load, supporting hepatic encephalopathy management.
Bifidogenic Effect & Microbiota Modulation
As the original "bifidogenic factor", LOSWIFT™Lactulose is selectively utilized by beneficial Bifidobacterium and Lactobacillus species while inhibiting the growth of putrefactive and pathogenic bacteria such as clostridia and Salmonella, helping to restore and maintain a balanced gut microbiome.
Enhanced Calcium and Magnesium Absorption
The short-chain fatty acids produced by LOSWIFT™Lactulose fermentation lower colonic pH, increasing the solubility and bioavailability of calcium, magnesium, and other minerals, with positive implications for bone health.
Application Advantages
First-Choice Safe Ingredient for Constipation Relief
Relieves constipation through the dual mechanism of osmotic action and probiotic fermentation, without stimulating intestinal nerves, inducing melanosis coli, or causing drug dependency. Its safety profile supports use by infants, children, pregnant women, adults, and the elderly.
Standard Ingredient for Hepatic Encephalopathy
Recommended by major hepatology guidelines worldwide, LOSWIFT™Lactulose is a compliant and effective functional ingredient for liver-support supplements, hepatoprotective health foods, and foods for special medical purposes (FSMP) targeting ammonia management.
Established Prebiotic Partner in Synbiotic Formulations
As the first commercial prebiotic, LOSWIFT™ pairs efficiently with Bifidobacterium and Lactobacillus strains in synbiotic ("probiotic + prebiotic") systems, suitable for infant formula, children's probiotic powders, and gut-health capsules in diverse dosage forms.
Mineral-Absorption Booster for Bone and Skeletal Health
By lowering colonic pH, LOSWIFT™Lactulose supports the absorption of calcium, magnesium, and other minerals, making it a valuable functional ingredient for middle-aged and senior osteoporosis-prevention products as well as prenatal and pediatric mineral supplements.
Real-World Applications
Product Information
Brand: Enemon Laxemon | Company: Jata Emona
A convenient wellness supplement in a gummy bear delivery format, certified by GMP, featuring a clean and simplified ingredient list with no artificial colours.
Key Ingredients
LOSWIFT™Lactulose Value
Gentle Bowel Movement Support: Precision-dosed at a low, daily-wellness level to gently increase intraluminal osmotic pressure and raise stool water content.
Microbiome Balance: Its bifidogenic activity promotes beneficial bacteria and suppresses harmful species, supporting a balanced gut microbiome.
Format Repositioning: Transforms a clinically validated bowel-care ingredient into a convenient, "snack-like" format, overcoming traditional adherence limitations.
Product Information
Brand: Eliminal Gel | Company: Orisil-Farm
A ready-to-eat 20 g stick-pack gel format designed for modern busy lifestyles, providing a non-GMO functional formulation for digestive health and detoxification.
Key Ingredients
LOSWIFT™Lactulose Value
Prebiotic Pillar: Serves as the prebiotic component of a "sorbent + prebiotic + antioxidant" three-pronged gut-purification system to bind, rebalance, and protect.
Selective Microflora Fuel: Selectively fuels the growth of bifidobacteria and lactobacilli while suppressing putrefactive species in the gut.
Synergistic Cleansing: Paired with silicon dioxide to deliver a clinically meaningful sorbent and prebiotic synergy that balances intestinal pH and enhances absorption.
Company Introduction
Leading Global Manufacturer of Functional Sweeteners Since 1997
Baolingbao Biotechnology Co., Ltd. is a leading global manufacturer specializing in the R&D, manufacturing, and solution services of functional carbohydrates. Founded in 1997, we are focused on enzyme engineering and fermentation engineering, serving customers across more than 100 countries and regions worldwide.
In 2009, we became the first functional sugar company listed on the Shenzhen Stock Exchange (Stock Code: 002286) in China's A-share market. Today, we have established deep strategic partnerships with major global customers including Coca-Cola, Danone, Yili Group, and Perfect (China).The company operates on a site spanning 300 acres, with an annual production capacity of 600,000 tons and a workforce of 1,300 employees.
Advanced R&D Capabilities
Possessing 9 R&D platforms including national enterprise technology center, national-local joint engineering lab, and postdoctoral research workstation. Expert team composed of academicians, Taishan Scholars, and overseas experts.
Global Market Presence
Products exported to over 100 countries and regions worldwide. Strategic partnerships with majority of core customers across food, beverage, pharmaceutical, and dietary supplement industries.
World-Class Manufacturing
Baolingbao's production infrastructure is characterized by a high degree of automation, intelligence, and digitalization. The company has made substantial investments in key facilities, including drying towers, pharmaceutical-grade sugar production lines, digital erythritol plants, and intelligent stereo warehouses. Featuring internationally sourced technologies and advanced control systems, these initiatives have enhanced production efficiency, reduced energy consumption, and enabled full traceability across the supply chain.In support of sustainable operations, Baolingbao manages 40,000 mu (approximately 2,667 hectares) of regenerative agricultural planting bases and generates 10 million kWh of photovoltaic power annually.
Comprehensive Quality Assurance
First batch to pass FDA on-site audit. Certified with GMP, GRAS, HALAL, Kosher, Organic (US & EU standards), ISO9001/22000/14000/45001. End-to-end food safety from farm to table.
Innovation & Industry Leadership
Over 260 patent applications submitted with 97 patents granted and more than 70 core technologies developed. Actively participated in formulation of 1 international standard and over 30 national standards.
Contact Us
baolingbao@blb-cn.com
