Applications of Lactulose in Food and Pharmaceutical Industry
Synthetic nondigestible disaccharide
Excellent prebiotic activity ("bifidogenic factor")
Thermal and acid stability
Low glycemic index
Applications of Lactulose in Food and Pharmaceutical Industry
What is LOSWIFT™Lactulose?
Synthetic Prebiotic Disaccharide
LOSWIFT™Lactulose (4-O-beta-D-galactopyranosyl-D-fructose) is a synthetic, non-digestible disaccharide produced almost exclusively through the alkaline isomerization of lactose. It appears as a white, odourless powder with a mild sweet taste and a molar mass of 342.30 g/mol.
Because mammals lack the specific disaccharidase required to hydrolyze it in the small intestine, LOSWIFT™Lactulose reaches the colon essentially intact. There, it serves as an efficient substrate for saccharolytic bacteria, particularly Bifidobacterium and Lactobacillus species.
This unique biochemical behavior forms the foundation for its dual role as a high-value prebiotic ingredient in functional food development and as a pharmacologically active substance registered in over 100 countries.
Health Benefits
Osmotic Laxative Effect
Fermentation by colonic bacteria produces organic acids that lower gut pH and increase osmotic pressure, drawing water into the bowel to promote peristalsis and treat chronic constipation safely without causing cramping or electrolyte disturbances.
Blood Ammonia Reduction
Stimulates bacterial growth to utilize nitrogen for protein synthesis while luminal acidification converts diffusible ammonia (NH3) into non-diffusible ammonium (NH4+), facilitating its excretion and managing hepatic encephalopathy.
Enhancement of Mineral Absorption
Promotes intestinal uptake and retention of essential minerals, significantly boosting calcium and magnesium absorption to support skeletal health and bone density without directly altering bone turnover rates.
Prebiotic Action & Microbial Balance
Selectively stimulates the proliferation of beneficial Bifidobacteria and Lactobacilli while inhibiting pathogenic species such as Clostridium and E. coli, strengthening mucosal barrier function and modulating immune response.
Application Advantages
Versatile Prebiotic Fortification
Easily incorporated into infant formulas, soy milk, and dairy products like yogurt to shift microbial profiles toward beneficial bacterial dominance, encouraging healthy gut flora colonization without altering sensory properties or storage acceptability.
Inhibition of Harmful Metabolites
Creates a low-pH intestinal environment that suppresses bacterial enzymes responsible for secondary bile acid formation (such as deoxycholic acid), thereby mitigating gut-derived endotoxins and reducing potential colorectal carcinogenic risks.
High Thermal & Storage Stability
Demonstrates outstanding stability during food processing and extended storage conditions, making it an ideal functional ingredient for heat-treated nutrition formulas, fermented beverages, and dietary supplements.
Proven Physiological Safety
Relies entirely on natural physiological fermentation pathways rather than chemical irritation, providing a gentle and well-tolerated functional health upgrade suitable for sensitive populations including infants, diabetics, and the elderly.
Company Introduction
Leading Global Manufacturer of Functional Sweeteners Since 1997
Baolingbao Biotechnology Co., Ltd. is a leading global manufacturer specializing in the R&D, manufacturing, and solution services of functional carbohydrates. Founded in 1997, we are focused on enzyme engineering and fermentation engineering, serving customers across more than 100 countries and regions worldwide.
In 2009, we became the first functional sugar company listed on the Shenzhen Stock Exchange (Stock Code: 002286) in China's A-share market. Today, we have established deep strategic partnerships with major global customers including Coca-Cola, Danone, Yili Group, and Perfect (China).The company operates on a site spanning 300 acres, with an annual production capacity of 600,000 tons and a workforce of 1,300 employees.
Advanced R&D Capabilities
Possessing 9 R&D platforms including national enterprise technology center, national-local joint engineering lab, and postdoctoral research workstation. Expert team composed of academicians, Taishan Scholars, and overseas experts.
Global Market Presence
Products exported to over 100 countries and regions worldwide. Strategic partnerships with majority of core customers across food, beverage, pharmaceutical, and dietary supplement industries.
World-Class Manufacturing
Baolingbao's production infrastructure is characterized by a high degree of automation, intelligence, and digitalization. The company has made substantial investments in key facilities, including drying towers, pharmaceutical-grade sugar production lines, digital erythritol plants, and intelligent stereo warehouses. Featuring internationally sourced technologies and advanced control systems, these initiatives have enhanced production efficiency, reduced energy consumption, and enabled full traceability across the supply chain.In support of sustainable operations, Baolingbao manages 40,000 mu (approximately 2,667 hectares) of regenerative agricultural planting bases and generates 10 million kWh of photovoltaic power annually.
Comprehensive Quality Assurance
First batch to pass FDA on-site audit. Certified with GMP, GRAS, HALAL, Kosher, Organic (US & EU standards), ISO9001/22000/14000/45001. End-to-end food safety from farm to table.
Innovation & Industry Leadership
Over 260 patent applications submitted with 97 patents granted and more than 70 core technologies developed. Actively participated in formulation of 1 international standard and over 30 national standards.
Contact Us
baolingbao@blb-cn.com
