Applications of LOSWIFT Lactulose in Medicine and Pharmacy
Lactulose as main component
mixed sugar solution
prebiotic properties
promotes intestinal health
Applications of LOSWIFT Lactulose in Medicine and Pharmacy
What is LOSWIFT™Lactulose?
Bridging Prebiotic Function and Clinical Application
LOSWIFT™Lactulose (4-O-β-D-galactopyranosyl-D-fructose) is a synthetic, non-digestible disaccharide that does not occur naturally. Produced almost exclusively today through alkaline isomerization of lactose, the glucose unit of lactose is rearranged into a fructose unit under basic conditions.
It appears as a white, odourless powder with a mild sweet taste and serves as an important functional ingredient. Although simple in structure, mammals lack the specific disaccharidase needed to hydrolyze it in the small intestine, allowing it to reach the colon essentially intact.
In the colon, it becomes an efficient substrate for saccharolytic bacteria, particularly Bifidobacterium and Lactobacillus species, making it registered as a medicinal product in more than 100 countries.
Health Benefits
Osmotic Laxative Effect
Passes unchanged to the colon, where bacteria metabolise it into short-chain fatty acids. This increases osmotic pressure, draws water into the intestinal tract, and stimulates peristalsis without causing intestinal cramps.
Blood Ammonia Reduction
Acidifies the colon to trap ammonia as non-absorbable NH₄⁺ and diverts nitrogen into microbial biomass, serving as a first-line agent in managing hepatic encephalopathy.
Inhibition of Secondary Bile Acids
Promotes the growth of Bifidobacterium and acidifies the colonic environment, significantly decreasing the concentration and excretion of tumor-promoting secondary bile acids.
Mineral Absorption Enhancement
Efficiently improves the intestinal absorption and retention of essential minerals, particularly calcium and magnesium, supporting bone health.
Application Advantages
Chemical Synthesis
Industrial production relies on alkaline isomerization using homogeneous or heterogeneous catalysts, converting lactose into LOSWIFT™Lactulose via established transformations.
Enzymatic Synthesis
Utilizes β-galactosidases for transgalactosylation, offering cleaner product profiles, milder production conditions, and a natural classification.
Electro-activation Synthesis
An innovative electrolysis reactor process that generates the required alkaline medium in situ, avoiding chemical catalysts and providing easier purification.
Prebiotic Action
Selectively increases beneficial Lactobacilli and Bifidobacteria populations while lowering luminal pH and reinforcing the intestinal barrier.
Company Introduction
Leading Global Manufacturer of Functional Sweeteners Since 1997
Baolingbao Biotechnology Co., Ltd. is a leading global manufacturer specializing in the R&D, manufacturing, and solution services of functional carbohydrates. Founded in 1997, we are focused on enzyme engineering and fermentation engineering, serving customers across more than 100 countries and regions worldwide.
In 2009, we became the first functional sugar company listed on the Shenzhen Stock Exchange (Stock Code: 002286) in China's A-share market. Today, we have established deep strategic partnerships with major global customers including Coca-Cola, Danone, Yili Group, and Perfect (China).The company operates on a site spanning 300 acres, with an annual production capacity of 600,000 tons and a workforce of 1,300 employees.
Advanced R&D Capabilities
Possessing 9 R&D platforms including national enterprise technology center, national-local joint engineering lab, and postdoctoral research workstation. Expert team composed of academicians, Taishan Scholars, and overseas experts.
Global Market Presence
Products exported to over 100 countries and regions worldwide. Strategic partnerships with majority of core customers across food, beverage, pharmaceutical, and dietary supplement industries.
World-Class Manufacturing
Baolingbao's production infrastructure is characterized by a high degree of automation, intelligence, and digitalization. The company has made substantial investments in key facilities, including drying towers, pharmaceutical-grade sugar production lines, digital erythritol plants, and intelligent stereo warehouses. Featuring internationally sourced technologies and advanced control systems, these initiatives have enhanced production efficiency, reduced energy consumption, and enabled full traceability across the supply chain.In support of sustainable operations, Baolingbao manages 40,000 mu (approximately 2,667 hectares) of regenerative agricultural planting bases and generates 10 million kWh of photovoltaic power annually.
Comprehensive Quality Assurance
First batch to pass FDA on-site audit. Certified with GMP, GRAS, HALAL, Kosher, Organic (US & EU standards), ISO9001/22000/14000/45001. End-to-end food safety from farm to table.
Innovation & Industry Leadership
Over 260 patent applications submitted with 97 patents granted and more than 70 core technologies developed. Actively participated in formulation of 1 international standard and over 30 national standards.
Contact Us
baolingbao@blb-cn.com
